B-type natriuretic peptide levels: diagnostic and prognostic in congestive heart failure: what's next?
نویسنده
چکیده
Although major advances in our understanding of the pathophysiology of congestive heart failure (CHF) have resulted in treatments that lead to symptomatic improvement and longer life, CHF still remains a major clinical challenge, especially in the areas of diagnosis, prognosis, and risk stratification. For the first time since the introduction of echocardiography some 20 years ago, a simple blood test appears to offer a significant advance in these areas.
منابع مشابه
Clinical and Biochemical Assessments of Circulating B-Type Natriuretic Peptide as a Useful Marker in Pediatric Cardiac Patients
Background Although the left ventricle is the major site of BNP secretion in response to cardiac pressure or volume overload, the myocytes of both atria and ventricles secrete B- type natriuretic peptide (BNP). This study aimed to assess and compare the plasma levels of BNP in common pediatric cardiac diseases to clarify its pathophysiological role and evaluate its po...
متن کاملB-type natriuretic peptide: a diagnostic, prognostic, and therapeutic tool in heart failure.
B-type natriuretic peptide is a neurohormone secreted from the cardiac ventricles in response to ventricular stretch and pressure overload. It counteracts the vasoconstriction that occurs as a compensatory mechanism in heart failure. A new test for measuring plasma levels of B-type natriuretic peptide can help in the diagnosis and treatment of patients with congestive heart failure. Dyspnea ass...
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Background Heart failure is a major cause of death in thalassemia. The study aimed to determine the diagnostic value of N Terminal Pro B Type Natriuretic Peptide (NT-pro BNP), to early diagnose the cardiac involvement in beta- thalassemia major patients. Materials and Methods 80 thalassemia patients aged 7 to 18 years old (patients group), and 80 healthy age and gender matched controls were ...
متن کاملB-type natriuretic levels in critically ill patients: critically misleading?
Although B-type natriuretic peptide (BNP) has been used for the diagnosis of congestive heart failure in many clinical settings, its diagnostic role in critically ill patients remains uncertain. The body of literature suggests that BNP and N-terminal pro-BNP levels are not useful for the diagnosis of systolic or diastolic heart failure in the critically ill, including in patients with brain hem...
متن کاملB-type natriuretic peptide: a review of its diagnostic, prognostic, and therapeutic monitoring value in heart failure for primary care physicians.
BACKGROUND Congestive heart failure is misdiagnosed clinically 50% to 75% of the time. B-type natriuretic peptide (BNP) concentrations have shown to be useful in the diagnosis of heart failure in addition to having prognostic and therapeutic monitoring value. Studies were evaluated for validity and potential value of BNP measurements for managing patients with heart failure. METHODS A literat...
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عنوان ژورنال:
- Circulation
دوره 105 20 شماره
صفحات -
تاریخ انتشار 2002